bt4002_2025T1_Q1_NA.pdf
Big Data and Biological Networks · Quiz 1 · Jan 2025
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Questions and published explanations below are available without starting a test. Some questions may not have a published solution yet.
Question 8 MCQ · 1.0 marks
The bond between a phosphate group and the ribose sugar group in RNA is called which of the
following?
Peptide bond
Glycosidic bond
Phosphodiester bond
Amide bond
A published solution is not available for this question yet.
Question 9 MCQ · 1.0 marks
Translation is the process by which:
DNA gets converted to chromosomes
RNA gets converted to protein
Protein folding occurs to produce functional enzymes
Cells produce ATP
A published solution is not available for this question yet.
Question 10 MCQ · 1.0 marks
Which of the following is not true :
Genomics data is independent of the cell type
Transcriptomics data is dependent on a specific cell type
Both genomics data is independent of the cell type and transcriptomics data is
dependent on a specific cell type are true
None of these statements are true
A published solution is not available for this question yet.
Question 11 MCQ · 1.0 marks
What is the primary advantage of Next-Generation Sequencing (NGS) over traditional Sanger
sequencing?
Longer read lengths.
Higher accuracy.
Higher throughput.
Lower cost per base.
A published solution is not available for this question yet.
Question 12 MCQ · 1.0 marks
What do the term Okazaki fragments refer to?
Short fragments of DNA created before transcription
Byproducts of histone modifications
Short fragments of DNA created during replication on the 5’ to 3’ template
strand
Short fragments of DNA created during replication on the 3’ to 5’ template
strand
A published solution is not available for this question yet.
Question 13 MCQ · 1.0 marks
Which of the following proteins is required for transcription:
DNA polymerase
Sigma factor
Uracilase
Ribonuclease
A published solution is not available for this question yet.
Question 14 MSQ · 2.0 marks
Which of the following experiments fall under the purview of epigenomics?
DNA methylation
Chromatin accessibility
Genome wide association studies
Differential expression analysis
A published solution is not available for this question yet.
Question 15 MSQ · 2.0 marks
[[IMAGE:1cc32e9731e311fb_4_0]]

A - 2, B - 1, C - 4, D - 3
A - 4, B - 2, C - 1, D - 3
A - 3, B - 2, C - 1, D - 3
A - 3, B - 2, C - 1, D - 4
A published solution is not available for this question yet.
Question 16 MSQ · 2.0 marks
Consider the following and select the correct option.
**Assertion**: Genomics can be used to identify individuals predisposed to certain diseases.
**Reason**: By analyzing an individual's DNA, specific genetic variations associated with increased
disease risk can be detected.
Both the assertion and reason are correct, and the reason is a correct
explanation of the assertion.
Both the assertion and reason are correct, but the reason is not a correct
explanation of the assertion.
The assertion is correct, but the reason is incorrect.
The assertion is incorrect, but the reason is correct.
A published solution is not available for this question yet.
Question 17 MSQ · 2.0 marks
Which of the following statements are true:
Transcription uses two strands of DNA
Polyadenylation does not happen in prokaryotic cells
Intronic genes are only present in eukaryotic cells
Proteins are produced in the nuclei
A published solution is not available for this question yet.
Question 18 MSQ · 2.0 marks
Application of genomics include:
Identifying individuals based on DNA evidence
Tracking the spread of infectious diseases
Predictive testing for genetic diseases
Identifying genetic diversity within species
A published solution is not available for this question yet.
Question 19 NAT · 1.0 marks
[[IMAGE:1cc32e9731e311fb_6_1]]
Based on the above data, answer the given subquestions.
What is the id number of the most significant SNP?

A published solution is not available for this question yet.
Question 20 NAT · 1.0 marks
[[IMAGE:1cc32e9731e311fb_6_1]]
Based on the above data, answer the given subquestions.
From the plot, what would be the number of SNPs considered for this analysis? (Give 5% range
above and below)

A published solution is not available for this question yet.
Question 21 NAT · 1.0 marks
[[IMAGE:1cc32e9731e311fb_6_1]]
Based on the above data, answer the given subquestions.
How many causal SNPs are present in the figure?

A published solution is not available for this question yet.
Question 22 SHORT_TEXT · 3.0 marks
[[IMAGE:1cc32e9731e311fb_8_2]]
**NOTE:** Enter the exact answer without any extra space in the beginning or at the end.

A published solution is not available for this question yet.
Question 23 SHORT_TEXT · 3.0 marks
[[IMAGE:1cc32e9731e311fb_9_3]]
**NOTE:** Enter the exact answer without any extra space in the beginning or at the end.

A published solution is not available for this question yet.
Question 24 MCQ · 2.0 marks
[[IMAGE:1cc32e9731e311fb_10_4]]
What is the clustering coefficient of the given graph?

0.67
0.50
0.31
0.44
A published solution is not available for this question yet.
Question 25 MCQ · 2.0 marks
[[IMAGE:1cc32e9731e311fb_10_5]]
What is the mean degree of this undirected graph?

1/3
4/3
8/3
2/3
A published solution is not available for this question yet.
Question 26 MCQ · 2.0 marks
[[IMAGE:1cc32e9731e311fb_11_6]]

AttributeError: 'Graph' object has no attribute 'add_edge'
TypeError: 'DiGraph' object is not subscriptable
NetworkXError: Graph is immutable
[2]
A published solution is not available for this question yet.
Question 27 MCQ · 2.0 marks
[[IMAGE:1cc32e9731e311fb_11_7]]

[[IMAGE:1cc32e9731e311fb_11_8]]

[[IMAGE:1cc32e9731e311fb_11_9]]

[[IMAGE:1cc32e9731e311fb_11_10]]

[[IMAGE:1cc32e9731e311fb_11_11]]

A published solution is not available for this question yet.
Question 28 MSQ · 3.0 marks
Which of the following statements about bipartite graphs is TRUE?
In a bipartite graph, there are two disjoint sets of vertices such that no two
vertices within the same set are adjacent.
Every complete bipartite graph has an Eulerian circuit.
A bipartite graph can be colored with two colors such that no two adjacent
nodes have the same color.
In the adjacency matrix of a bipartite graph, the values corresponding to
edges within the same set of nodes will not all be zero.
A published solution is not available for this question yet.
Question 29 MSQ · 3.0 marks
Which of the following statements are true about the behavior of random and small-world
networks?
In a small-world network, as the rewiring probability p increases, the average
path length decreases dramatically.
Random networks tend to have high clustering coefficients compared to small-
world networks for small p.
In a small-world network, increasing the rewiring probability p makes the
network more disconnected and increases the clustering coefficient.
Small-world networks have a balance of high clustering and short average
path length for intermediate values of rewiring probability p.
A published solution is not available for this question yet.
Question 30 MSQ · 3.0 marks
Which of the following network models are suitable for representing the topology of metabolic
pathways in biological systems?
**Small-world network** because it ensures high clustering, which represents
functional metabolic clusters and pathways, while also having short path lengths for efficient
chemical signaling.
**Random network** because it randomly connects metabolites and enzymes,
ensuring diverse and unpredictable interactions in the network.
**Power-law network** because it produces a few highly connected nodes (hub
enzymes) that play crucial roles in regulating key metabolic pathways.
**Random network** because it results in efficient information transfer through
a uniform distribution of connections between metabolites and enzymes.
A published solution is not available for this question yet.
Question 31 MCQ · 2.0 marks
[[IMAGE:1cc32e9731e311fb_13_12]]
Calculate the betweenness centrality of node D in the network.

0.429
0.333
0.524
0.286
A published solution is not available for this question yet.
Question 32 MCQ · 2.0 marks
[[IMAGE:1cc32e9731e311fb_13_12]]
In the network shown, calculate the degree centrality of node E.

0.571
0.714
0.429
0.857
A published solution is not available for this question yet.
Question 33 MCQ · 2.0 marks
[[IMAGE:1cc32e9731e311fb_13_12]]
What is the density of this network?

0.464
0.393
0.500
0.429
A published solution is not available for this question yet.
Question 34 MCQ · 2.0 marks
[[IMAGE:1cc32e9731e311fb_13_12]]
Calculate the closeness centrality of node E.

0.538
0.636
0.583
0.500
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A published solution is not available for this question yet.