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Algorithmic Thinking in Bioinformatics · End Term · Jan 2025 · AN

Algorithmic Thinking in Bioinformatics · End Term · Jan 2025 AN

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Question 100 SHORT_TEXT · 1.0 marks

Assign consistent labels to all the edges and junctions in the 2D line drawing shown below. Enter the labels of the junctions 1, 2, 3, 4 in the text box, in that order. Or enter NIL if the drawing has no consistent label assignment.
Source diagram or notation
Enter a comma separated list of junction labels, or enter NIL. NO SPACES, TABS, DOTS, BRACKETS OR EXTRANEOUS CHARACTERS. **Answer format: X9,Y9,Z9,W9**

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Question 102 NAT · 4.0 marks

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Question 103 NAT · 4.0 marks

Source diagram or notation

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Question 104 MCQ · 4.0 marks

Source diagram or notation
6406534213194.Source diagram or notation
6406534213195.Source diagram or notation
6406534213196.Source diagram or notation
6406534213197.Source diagram or notation

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Question 105 MCQ · 4.0 marks

Source diagram or notation
6406534213198.Source diagram or notation
6406534213199.Source diagram or notation
6406534213200.Source diagram or notation
6406534213201.Source diagram or notation

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Question 106 MCQ · 4.0 marks

Source diagram or notation
6406534213202.Source diagram or notation
6406534213203.Source diagram or notation
6406534213204.Source diagram or notation
6406534213205.Source diagram or notation

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Question 107 MSQ · 4.0 marks

Source diagram or notation
6406534213206.Source diagram or notation
6406534213207.Source diagram or notation
6406534213208.Source diagram or notation
6406534213209.Source diagram or notation

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Question 108 NAT · 2.0 marks

The overlap graph of some linear (i.e., non-circular) genome Dna has 138 nodes. Answer the given subquestions about the de Bruijn graph constructed on the same set of k-mers. Remember that Dna can be reconstructed by using both the graphs when answering these questions.
What is the number of edges in the de Bruijn graph? Enter the value as a single integer.

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Question 109 NAT · 2.0 marks

The overlap graph of some linear (i.e., non-circular) genome Dna has 138 nodes. Answer the given subquestions about the de Bruijn graph constructed on the same set of k-mers. Remember that Dna can be reconstructed by using both the graphs when answering these questions.
What is the maximum number of nodes possible in the de Bruijn graph? Enter the value as a single integer.

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Question 110 MCQ · 3.0 marks

Answer the given subquestions.
What is the Burrows Wheeler Transform of the string ‘AACAAG$’?
6406534213212.
GCAAAA$
6406534213213.
G$CAAAA
6406534213214.
$GCAAAA
6406534213215.
$AACAAG

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Question 111 MCQ · 1.0 marks

Answer the given subquestions.
Is the transformed string more compressible using run-length encoding than the original string ?
6406534213216.
Yes
6406534213217.
No

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Question 112 NAT · 2.0 marks

Scientists of an alien world have used the UPGMA algorithm to construct the following Ultrametric tree (Figure 2) on six different species. The green nodes in the tree represent current-day species, while the red nodes represent their extinct ancestors. The numbers next to the red nodes represent the age of the node in million years.
Source diagram or notation
Based on the above data, answer the given subquestions.
During the construction of the phylogeny using the UPGMA algorithm, what was the average distance between the **species** represented by the nodes “N4” and “E”? Enter the value as a single integer.

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Question 113 NAT · 2.0 marks

Scientists of an alien world have used the UPGMA algorithm to construct the following Ultrametric tree (Figure 2) on six different species. The green nodes in the tree represent current-day species, while the red nodes represent their extinct ancestors. The numbers next to the red nodes represent the age of the node in million years.
Source diagram or notation
Based on the above data, answer the given subquestions.
How many million years ago did the species marked at the “N1” node diverge to form the descendants? Enter the value as a single integer.

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Question 114 NAT · 2.0 marks

Source diagram or notation
Based on the above data, answer the given subquestions.
Calculate the entropy for the fifth column? Round up the answer to 3 decimal places.

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Question 115 NAT · 2.0 marks

Source diagram or notation
Based on the above data, answer the given subquestions.
Source diagram or notation

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Question 116 NAT · 2.0 marks

Source diagram or notation
Based on the above data, answer the given subquestions.
Source diagram or notation

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Question 117 MCQ · 1.0 marks

Source diagram or notation
Based on the above data, answer the given subquestions.
The pooling layer in the DeepBIND model reduces the dimensionality of its input.
6406534213228.
TRUE
6406534213229.
FALSE

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Question 118 MCQ · 1.0 marks

Source diagram or notation
Based on the above data, answer the given subquestions.
Source diagram or notation
6406534213230.
TRUE
6406534213231.
FALSE

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Question 119 NAT · 3.0 marks

Source diagram or notation
Based on the above data, answer the given subquestions.
How many 6-mers in the sequence **GCTAGTCCATTGGA** have a nonzero probability of binding to the TF according to the PWM in the given table? Enter the answer as an integer.

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Question 120 MCQ · 3.0 marks

Source diagram or notation
Based on the above data, answer the given subquestions.
Which of the following substrings is least likely to be bound by the TF? Enter the answer as an integer.
6406534213223.Source diagram or notation
6406534213224.Source diagram or notation
6406534213225.Source diagram or notation
6406534213226.Source diagram or notation
      **MLT** **Section Id :** 64065387582

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